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Genital Tuberculosis – A Reason For Infertility Among Women

Tuberculosis continues to be a major health problem throughout the world affecting about 9.4 million people annually with about two million deaths. Over 95 % of new TB cases and deaths occur in developing countries with India and China together accounting for 40 % of the world’s TB burden.

Tuberculosis infection doesn’t always remain restricted to the lungs but can also travel to other parts of the body such as bones, joints, urinary tract and genital tract, etc. If it reaches the genital areas of a woman, it could lead to infertility. In developing countries like India Genital tract tuberculosis is identified as an important cause of infertility.

 

In such cases, IVF treatment from IVF centre becomes a ray of hope. Genital TB mainly affects females in the reproductive age group, but it is also reported in post-menopausal females.

How Genital Tuberculosis infection affects women’s chances of getting pregnant?

How Genital Tuberculosis infection affects women’s chances of getting pregnant?

 

  • When tuberculosis infection affects fallopian tubes, it may cause obstruction or dysfunction. This prevents the entry of fertilized egg into the uterus from tubes.
  • On the other hand, if bacteria erode lining of endometrium, it will become difficult for the fertilized egg to implant itself on uterus wall and hence again averting pregnancy.
  • Infection in the ovaries would affect quality of ovum or lead to failure in ovulation.
  • Infection in the cervix, vagina or vulva could also make chances of pregnancy bleak.

 

What are the symptoms of Genital tuberculosis?

 

Genital tuberculosis doesn’t show any visible symptoms usually. If a woman has suffered from pulmonary TB in the past then it can show following signs which can indicate sub-fertility.

 

  • Irregularity in menstrual cycles such as suffering from scanty or heavy periods
  • Pain and heaviness in the pelvic area
  • Cysts in pelvic area

 

How can Genital Tuberculosis be diagnosed?

Female Genital TB is usually asymptomatic and hence gets diagnosed when a female presents with infertility and all other causes have been ruled out. Some tests used for diagnosis are:

  1. endometrial biopsy
  2. culture of menstrual flow and laparoscopy
  3. polymerase chain reaction for the specific bacteria
  4. hysterosalpingographic study (HSG)

 

Treatment for Genital Tuberculosis

Usually treatment is by giving daily therapy of rifampicin (R), isoniazid (H), pyrazinamide (Z) and ethambutol (E) for 2 months followed by daily 4 month therapy of rifampicin (R) and isoniazid (H). 

Treatment for Genital Tuberculosis

Anti Tuberculosis Treatment (ATT) has an excellent recovery/cure rate, so patients should not lose hope after being diagnosed with the disease. 

Treatment must be given by an experienced physician and self medication is to be strictly avoided.

Post ATT treatment IVF-ET helps conceive if the endometrium of the patient is still healthy. However, if endometrium has been affected due to TB then adoption and surrogacy are the only options left. Best infertility clinic in Chandigarh, Panchkula and Mohali provide test tube baby treatment and surrogacy to such patients.

 

You can also visit our website Jannee Fertility Centre and follow us on Google Plus, Pinterest, Facebook, Twitter and YouTube for the latest blog on fertility issues. 

Make Healthy Choices to Enhance Your Chances Of Conceiving

Fertility problems have increased dramatically over the past twenty years. One in every six couples has difficulty achieving pregnancy and a quarter of all pregnancies end up in a miscarriage. Due to this, more and more couples nowadays are turning to fertility treatments. Best IVF treatment in Chandigarh is here to help you have a new family.

 

Infertility may be due to tubal damage, ovulatory dysfunction, endometriosis, low/nil sperm count, etc. However, in about 20% of infertility cases the cause of infertility may be unknown. This is known as “Unexplained Infertility”. Here, the need arises to look deeper at lifestyle factors and nutritional deficiencies.

 

Pre conception care –

Primordial sperm cells take at least three months to develop into a mature sperm. This means you need to have a three-month period before conceiving when you are trying to improve your fertility. This is called pre-conception period. Hormonal imbalances, detoxification of body, overcoming nutritional deficiencies- all of this can be achieved within this 3 to 6 month window prior to getting pregnant. So, you and your partner must embrace some lifestyle changes during this phase in order to achieve conception.

 

Choices to increase chances of conceiving:

Healthy diet to correct hormone imbalances –

Both you and your partner should follow a healthy diet in order to have a successful pregnancy. Healthy diet can help you correct hormone imbalances and improve sperm quality that may affect your ability to conceive.

 

Alcohol affects sperm health –

Drinking alcohol can reduce your fertility by half. Research has shown that drinking alcohol affects sperm health such as it causes a decrease in sperm count and an increase in abnormal sperm. So, it is better to stop drinking alcohol. If you are also suffering from male infertility problem, then you can go for IVF treatment in Chandigarh as the cost of IVF in Chandigarh is affordable.

 

Caffeine reduces fertility –

Research has shown that caffeine (particularly in the form of coffee) reduces fertility. So it is better to eliminate all caffeine-containing food and drinks including colas, chocolate, black teas and coffee for at least three months (preconception care).

 

Eliminate xenoestrogens with organic produce –

The most important thing which you need to do is to balance your hormones. During preconception period, you must avoid anything that might cause an imbalance. One such major culprit is the xenoestrogens. Eat as much organic produce as possible in order to eliminate an excess intake of xenoestrogens.

 

Smoking decreases sperm count –

Smoking affects fertility in women and can even bring on an early menopause. In males, it can decrease sperm count, making the sperm more sluggish. It even leads to decreased motility and DNA damage in sperms.

 

Exercise regime –

Start a moderate exercise regime to improve the blood flow through your body, especially your reproductive organs. Walk, yoga or moderate work out at the gym is recommended.

You can also visit our website Jannee Fertility Centre and follow us on Google Plus, Pinterest, Facebook, Twitter and YouTube for the latest blog on fertility issues. 

Jannee Fertility Team now available at Sangha Hospital, Ropar every Friday

Keeping in view the increasing demand for a fertility specialist in Ropar, Dr. Nirmal Bhasin, Director Jannee Fertility Centre, has started Infertility  OPD at Sangha Hospital. You will get the best treatment of in vitro fertilisation, Chandigarh. She and her team would be available there on every Friday of the month from 12 noon to 3 pm w.e.f. 9 December 2016.

You can also visit our website Jannee Fertility Centre and follow us on Google Plus, Pinterest, Facebook, Twitter and YouTube for the latest blog on fertility issues. 

Diminished Ovarian Reserve – What You Need to Know

Ovarian reserve can be defined as the quality and the quantity of the oocytes (eggs) in the ovaries. Diminished Ovarian Reserve (DOR) is defined as reduced capacity of the ovaries to produce oocytes (eggs). The oocytes produced by a woman with DOR are usually of poorer quality as compared to those produced by females with good ovarian reserve. Couples who are unable to conceive and plan to consult a fertility clinic must be tested for the female partner’s ovarian reserve. IVF clinics in Chandigarh conduct this test when a patient initially comes for a consultation.

Age of the female is the one of the most important factors in determining the quality and quantity of oocytes produced in an IVF cycle. This directly affects the chances of pregnancy. As a woman grows older, her ovarian reserve and her ability to conceive decrease both in natural cycle and assisted reproductive techniques cycle.

Decline in the ovarian reserve may put a woman at risk of poor performance in assisted reproductive techniques like IUI, IVF (test-tube baby). The most severe form of Diminished Ovarian Reserve (DOR) is represented by Premature Ovarian Failure (POF – Early Menopause) in young females.

Nowadays, with the increase in success rates of cancer treatment in children and in young women, the incidence of POF is rapidly rising. Age is considered to be the main cause of reduced ovarian reserve in a woman over 40 years of age, but as it is known, a premature reduction of ovarian reserve can also occur in young age. POF can occur spontaneously which is primary POF, or can be secondary to the consequence of chemotherapy, radiation, or surgery. Primary POF is because of unknown reasons in about 90% of cases.

Diminished Ovarian Reserve

RISK FACTORS & CAUSES OF EARLY MENOPAUSE/ POF

  1. Cigarette smoking
  2. Hypothyroidism (Increased TSH)
  3. Diabetes Mellitus
  4. Rheumatoid Arthritis
  5. Ovarian Surgeries
  6. Chemotherapy
  7. Infections like Herpes and Mumps

 
HOW TO DIAGNOSE DIMINISHED OVARIAN RESERVE (DOR)

Most of the women with DOR have normal menstruation at the time of diagnosis. However, some may experience decreased menstrual flow or delayed cycles. Ultimately, DOR may result into early menopause or POF. Such patients may present with symptoms of flushing and sweats, depressive mood, and vaginal dryness.

Ovarian Reserve may be diagnosed based on:-

  • Absence of periods for more than 3 months
  • High levels of Follicle Stimulating Hormone (FSH)
  • Low estrogen levels
  • Low AMH level
  • Low Antral Follicle Count (immature eggs count in ovary) through Ultrasound

 
The assessment of ovarian reserve has an important role in the management of patients with infertility. Clinically, the patient’s age and menstrual cycle pattern give a fair idea about the patient’s ovarian reserve.

CAN PATIENTS WITH DIMINISHED OVARIAN RESERVE CONCEIVE?

The only method of achieving pregnancy in DOR patients is by means of assisted reproductive techniques like – Artificial Insemination (IUI), In Vitro Fertilization (IVF), and In Vitro Fertilization with Donor Eggs. Women with severely DOR or POF benefit best by donor oocyte program.

To conclude, it is always wise to predict the patients likely to have a compromised ovarian reserve and provide proper counseling about the available options. A heartwarming emotional support by the treating doctor at Test Tube Baby clinics in Chandigarh provides miraculous psychological benefit to the patients.

You can also visit our website Jannee Fertility Centre and follow us on Google Plus, Pinterest, Facebook, Twitter and YouTube for the latest blog on fertility issues.

IVF Chandigarh

IVF Chandigarh